RenalKidneyUptakeCalculationHelper

Utility description: Renal Kidney Uptake Calculation Helper

Renal Kidney Uptake Calculation Helper — Renal Kidney Uptake Calculation Helper

ℹ️  Utility calculates quantitative renal function parameters:
    • Left and right kidney uptake percentage
    • Total Uptake
    • Asymmetry Index
    • Depth and background correction

⚠️  CRITICAL: Without depth correction, results are distorted!
    Deeper kidney will appear less active.

Usage:
  RenalKidneyUptakeCalculationHelper.exe                            → demo mode (console output)
  RenalKidneyUptakeCalculationHelper.exe input.csv output.json      → evaluate your data

Input format:
BatchNumber,ProductName,Left_Counts,Right_Counts,BG_Counts,Dose_MBq,Calib_Factor,Atten_Coeff,Left_Depth_cm,Right_Depth_cm,Min_Total_Uptake,Max_Asymmetry

Example:
  RENAL-001,Tc-99m DMSA,150000,145000,500,200,150,0.15,7.0,7.2,40,15

— WHY IS THIS NEEDED?
Quantitative assessment is critical for kidney disease diagnostics:
• DMSA is used to assess cortical mass and detect scarring (pyelonephritis)
• MAG3 and DTPA are used to assess filtration and secretion rates
• Gamma camera registers only surface photons; deep structures are "shadowed"
• Asymmetry >15% often indicates renal artery stenosis or chronic disease
• Utility automates complex calculations accounting for background and signal attenuation

⚠️  CRITICAL:
• Background Subtraction is mandatory for accuracy
• Attenuation Correction uses soft tissue attenuation coefficient (~0.15 cm^-1 for 140 keV)
• System calibration factor must be current
• Normal total uptake for DMSA is 40-50% of administered dose

Key features:
• Net Counts calculation
• Exponential depth attenuation correction
• Asymmetry Index calculation
• Support for various radiopharmaceuticals (DMSA, MAG3, DTPA)

Critical parameters:
• Total Uptake: ≥40% (for DMSA)
• Asymmetry: ≤15%

💡 Usage tips:
1. Precisely define ROI (Regions of Interest) around kidneys
2. Measure kidney depth via CT data or formulas based on height/weight
3. Use standardized background subtraction protocols (subrenal region)
4. Compare results with patient's previous studies
5. Account for time post-injection (for DMSA peak uptake is 2-4 hours)

⚠️ Note: Unlike simple visualization, this tool turns pictures into numbers. This allows objective tracking of disease progression or treatment efficacy, not relying solely on subjective physician opinion.